Like a number of other East Asian languages, Japanese uses a complex system of honorifics, i.e. a system where a number of different levels of politeness are expressed in language via words, word forms or grammatical constructs. These can range from addressing someone or referring to someone with contempt (very informal) to expressing the highest level of reference (as used in addressing or referring to God) or any number of levels in-between.

One way to do this is through the usage of lexical honorific forms, i.e., completely different words, as shown here in the widely-used Japanese Shinkaiyaku (新改訳) Bible of 2017. Here, nasaru (なさる), the respectful form of suru (する) or “do” is used.

Other uses of honorifics in this verse include:

• The choice of a benefactive construction. Here, -naide (ないで) or “do not (for their sake)” is used in combination with kudasaru (くださる), a respectful form of the benefactive kureru (くれる). A benefactive reflects the good will of the giver or the gratitude of a recipient of the favor. To convey this connotation, English translation needs to employ a phrase such as “for me (my sake)” or “for you (your sake).”
• The usage of an honorific construction where the morphemes rare (られ) or are (され) are affixed on the verb. This is particularly done with verbs that have God as the agent to show a deep sense of reverence. Here, nozom-are-ru (望まれる) or “desire/hope” is used.
• The choice of a benefactive construction. Here, yō ni shite (ようにして) or “do so (so that) / make it like” is used in combination with kudasaru (くださる), a respectful form of the benefactive kureru (くれる). A benefactive reflects the good will of the giver or the gratitude of a recipient of the favor. To convey this connotation, English translation needs to employ a phrase such as “for me (my sake)” or “for you (your sake).”

(Source: S. E. Doi, see also S. E. Doi in Journal of Translation, 18/2022, p. 37ff. )